Open an ADMINISTRATOR LEVEL command prompt, type in the path of the patch.exe file, then press enter. It should run the patch right after that.
Example: my patch file was located at C:\Users\Medstar\Downloads\KanesWrath_english_patch1.02.exe
In the command prompt, I would put the following: "C:\Users\Medstar\Downloads\KanesWrath_english_patch1.02.exe"
Then I would press the "enter" key.